Amniotic Membrane Products Explained: Health Benefits, Uses, and Innovations

Healing chronic wounds, preserving vision, and repairing damaged tissue are some of the most pressing challenges in modern healthcare. Amniotic membrane products — especially those featuring dual layer membrane technology — offer a regenerative, low-risk option that’s transforming care across medical disciplines.

Whether you’re a provider seeking better healing tools or a patient exploring innovative therapies, understanding how these products work can help you make more informed decisions.

What Are Amniotic Membrane Products?

Amniotic membrane products are biologic grafts derived from the innermost layer of the placenta. These tissues are thoroughly screened, cleaned, and preserved for clinical use — all while retaining their powerful healing properties.

A standout advancement in this category is the dual layer membrane, which includes both the amnion and chorion layers. This design enhances durability and extends the release of growth factors critical for tissue regeneration.

Why Health Providers Trust Dual Layer Membranes

Amniotic membrane products are gaining widespread adoption for one reason: results. When standard therapies don’t work — especially in cases of chronic or complex wounds — these natural biologics can support faster, more complete healing.

Clinical Benefits:

• Reduces inflammation and pain

• Promotes cellular regeneration and tissue repair

• Lowers risk of infection

• Minimizes scarring

• Safe for use without immunosuppressants

Dual layer membranes offer longer biological activity and greater structural integrity, making them ideal for difficult-to-treat wounds and surgical applications.

Common Uses in Healthcare

Amniotic membrane and dual layer membrane products are used across a range of clinical settings:

1. Wound Care

Applied as biologic dressings for:

• Diabetic foot ulcers

• Pressure injuries

• Venous leg ulcers

Dual layer membranes provide enhanced coverage and durability, improving outcomes for patients with stubborn or non-healing wounds.

2. Ophthalmology

Used in procedures such as:

• Pterygium removal

• Corneal ulcers

• Chemical burns

Cryopreserved or dehydrated membranes protect the eye, reduce inflammation, and promote epithelial regrowth.

3. Orthopedics & Sports Medicine

Utilized for:

• Tendonitis

• Joint degeneration

• Ligament injuries

Injectable and patch-form amniotic products offer a regenerative alternative to corticosteroids and surgery.

4. Plastic and Reconstructive Surgery

Used to:

• Reduce scarring

• Support graft integration

• Accelerate recovery after cosmetic or reconstructive procedures

Dual layer membranes are especially useful where tissue strength and long-term healing support are essential.

Types of Amniotic Membrane Products

Clinicians can choose from several product types based on patient needs and treatment goals:

• Dehydrated membrane (dHACM): Room temperature stable, used in outpatient and surgical settings

• Cryopreserved membrane: Retains more natural biological components, often used in ophthalmology

• Dual layer membrane: Combines amnion and chorion for superior strength and prolonged healing support

• Injectable amniotic matrix: Used in orthopedics, sports medicine, and pain management

What Sets Dual Layer Membranes Apart?

Dual layer membrane products are designed to offer:

• Greater durability: Resists tearing and breakdown at the wound site

• Prolonged biological activity: Extended delivery of growth factors and cytokines

• Improved adherence and performance: Stays in place longer, enhancing clinical outcomes

• Broad versatility: Suitable for chronic wounds, burns, surgical repair, and more

These advantages make dual layer membranes a growing favorite in health systems looking to optimize healing timelines and reduce complications.

Are Amniotic Membrane Products Safe?

Yes. These products are regulated by the U.S. Food and Drug Administration (FDA) under the HCT/P (Human Cells, Tissues, and Cellular and Tissue-Based Products) framework. Leading manufacturers use rigorous donor screening, sterilization, and traceability protocols to ensure product safety.

Additionally, since amniotic tissue is immune-privileged, it typically does not trigger rejection or significant immune response.

Trusted Brands in the Health Space (2025)

A number of proven products are now widely used across hospitals, clinics, and surgical centers:

• EpiFix® by MiMedx – Dehydrated amniotic allograft for chronic wound care

• AmnioGraft® by Bio-Tissue – Cryopreserved membrane designed for ocular use

• Grafix® by Osiris Therapeutics – Placental membrane used in advanced wound therapy

• AmnioExcel® Plus Dual Layer Membrane by DermaSciences – Combines amnion and chorion for enhanced structural support

• ReNu® by Organogenesis – Injectable amniotic suspension for orthopedic conditions

• Acesso Biologics – Offers a full suite of amniotic membrane products used in wound care, surgery, and regenerative medicine

Acesso Biologics is known for its high-quality sourcing, stringent safety protocols, and growing presence in both outpatient and hospital-based care.

Final Thoughts: A New Era of Healing in Healthcare

Amniotic membrane products — and especially dual layer membranes — are helping to close treatment gaps in chronic wounds, soft tissue injuries, and surgical recovery. With their regenerative properties and excellent safety profile, they represent one of the most exciting innovations in health and healing today.

As technology advances and clinical evidence grows, expect to see even broader adoption of these biologics across specialties.